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Cultural control is the manipulation of the environment to avert serious pest damage. It depends on knowledge of both the plant's needs and its potential problems. For example, most plants have an ideal site in which they will flourish. In a poor site, they become stressed and prone to greater pest attack.
Avoid using key plants or "pest-prone plants." Other examples of key plants include skimmia (chronic spider mite problems), spruce (chronic aphid problems), and many crabapple varieties (powdery mildew and scab problems).
Genetic expressions (leaf type, toxins in plant) make certain varieties resistant to pests whereas others of the same species are quite susceptible. For example, many rose and crabapple varieties are disease resistant, and several rhododendron species and varieties are almost immune to leaf notching by root weevils. Ask known experts about them or consult extension publications.
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